Management of inappropriate sinus tachycardia with ivabradine in a renal transplant recipient.

Clinical efficacy of ivabradine in patients with inappropriate sinus tachycardia: a prospective, randomized, placebo-controlled, double-blind, crossover evaluation.

OBJECTIVES The purpose of this study was to investigate the role of ivabradine in the treatment of symptomatic inappropriate sinus tachycardia using a double-blind, placebo-controlled, crossover design. BACKGROUND Due to its I(f) blocking properties, ivabradine can selectively attenuate the high discharge rate from sinus node cells, causing inappropriate sinus tachycardia. METHODS Twenty-on...

Inappropriate sinus tachycardia: focus on ivabradine.

Inappropriate sinus tachycardia (IST) is an incompletely understood condition, characterised by an elevation in heart rate (HR) accompanied by wide ranging symptoms in the absence of an underlying physiological stimulus. The condition often takes a chronic course with significant adverse effects on quality of life. Currently, there is no effective treatment for IST. Beta-blockers, generally con...

Innappropriate Sinus Tachycardia After Superior Vena Cava Isolation In Addition To Pulmonary Veins Isolatin Of Paroxysmal Atrial Fibrillation Cryoballoon Ablation.

We report a case of persistent inappropriate sinus tachycardia (IST) after pulmonary vein and superior vena cava (SVC) isolation with cryoballoon ablation for paroxysmal atrial fibrillation (PAF). After the cryoballoon ablation (CBA) procedure, the patient presented with sinus tachycardia of 105 beats/minute. The patient was successfully treated with metoprolol and ivabradine therapy.

Heart rate reduction for 36 months with ivabradine reduces left ventricular mass in cardiac allograft recipients: a long-term follow-up study

BACKGROUND Due to graft denervation, sinus tachycardia is a common problem after heart transplantation, underlining the importance of heart rate control without peripheral effects. However, long-term data regarding the effects of ivabradine, a novel If channel antagonist, are limited in patients after heart transplantation. METHODS In this follow-up analysis, the resting heart rate, left vent...

A young renal transplant recipient with unexplained resting sinus tachycardia, hypertension and beta-blocker resistance.